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Fibromyalgia


BMC Musculoskeletal Disorders 2009, 10:162doi:10.1186/1471-2474-10-162

 

Research article

 

Cognitive impairment in patients with Fibromyalgia syndrome as assessed by the Mini-Mental State Examination

 

Jose Rodríguez-Andreu (1), Rosario Ibáñez-Bosch (2), Amparo Portero-Vázquez (3) , Xavier Masramon (4) , Javier Rejas (5) and Rafael Gálvez (6)

 

  1. Department of Rheumatology, Hospital Virgen de la Victoria, Málaga, Spain
  2. Department of Rheumatology, Hospital de Navarra, Pamplona, Spain
  3. Department of Rehabilitation, Hospital Xeral-CALDE, Lugo, Spain
  4. European Biometric Institute, Barcelona, Spain
  5. Health Outcomes Research Department, Medical Unit, Pfizer España, Alcobendas, Spain
  6. Pain and Palliative Care Unit, University Hospital Virgen de las Nieves, Granada, Spain

 

The electronic version of this article is the complete one and can be found online at:
http://www.biomedcentral.com/1471-2474/10/162

 

Published: 21 December 2009

 

© 2009 Rodríguez-Andreu et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

 

Background

This study evaluated the frequency of cognitive impairment in patients with Fibromyalgia syndrome (FMS) using the Mini Mental State Examination (MMSE).

Methods

We analyzed baseline data from all 46 patients with FMS and 92 age- and sex-matched controls per diagnosis of neuropathic (NeP) or mixed pain (MP) selected from a larger prospective study.

Results

FMS had a slight but statistically significant lower score in the adjusted MMSE score (26.9; 95% CI 26.7-27.1) than either NeP (27.3; 95% CI 27.2-27.4) or MP (27.3; 27.2-27.5). The percentage of patients with congnitive impairment (adjusted MMSE ≤ 26) was numerically higher in FMS (15%; 95% CI 6.3-29) compared with NeP (5%; 95% CI 1.8-12.2) or MP (5%; 95% CI 1.8-12.2) and higher than in the same age stratum of the general population (0.05%).

Conclusions

Compared with the population reference value, patients with FMS showed high frequency of cognitive impairment.

 

Full Text article at : http://www.biomedcentral.com/1471-2474/10/162

 

Also available as PDF document

 

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